Prevailing vitamin D status influences mitochondrial and glycolytic bioenergetics in peripheral blood mononuclear cells obtained from adults

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Prevailing vitamin D status influences mitochondrial and glycolytic bioenergetics in peripheral blood mononuclear cells obtained from adults

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作者：Emily K. Calton^a ; Kevin N. Keane^b ; Mario J. Soares^a ; ^{m.soares@curtin.edu.au" class="auth_mail" title="E-mail the corresponding author} ; Jordan Rowlands^b ; Philip Newsholme^b ; ^{philip.newsholme@curtin.edu.au" class="auth_mail" title="E-mail the corresponding author}
关键词：2DG ; 2-deoxyglucose ; BHI ; bioenergetic health index ; FM ; fat mass ; FFM ; fat free mass ; PBMCs ; peripheral blood mononuclear cells ; PPR ; proton production rate ; OCR ; oxygen consumption rate ; RQ ; respiratory quotient ; RMR ; resting metabolic rate ; UCP ; uncoupling proteins ; VDR ; vitamin D receptor
刊名：Redox Biology
出版年：2016
出版时间：December 2016
年：2016
卷：10
期：Complete
页码：243-250
全文大小：433 K

文摘

•: A model linking vitamin D status and the bioenergetic profile of PBMCs is proposed.
•: Adults with <50 nmol/L had greater oxidative and glycolytic metabolism.
•: Bioenergetic Health Index was positively related to fasting insulin sensitivity.

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