Integrated liquid chromatography method in enantioselective studies: Biodegradation of ofloxacin by an activated sludge consortium

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Integrated liquid chromatography method in enantioselective studies: Biodegradation of ofloxacin by an activated sludge consortium

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作者：Alexandra S. Maia^a ; ^b ; Paula M.L. Castro^b ; Maria Elizabeth Tiritan^a ; ^c ; ^d ; ^{elizabeth.tiritan@iscsn.cespu.pt" class="auth_mail" title="E-mail the corresponding author} ; ^{tiritan@yahoo.com.br" class="auth_mail" title="E-mail the corresponding author}
关键词：Ofloxacin ; Levofloxacin ; Macrocyclic antibiotic-based stationary phases ; Enantioselectivity ; Biodegradation ; Activated sludge
刊名：Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences
出版年：2016
出版时间：1 September 2016
年：2016
卷：1029-1030
期：Complete
页码：174-183
全文大小：1054 K

文摘

•: Evaluation of the enantioselective biodegradation of ofloxacin and levofloxacin by an activated sludge consortium.
•: Enantiomerization was observed in the biodegradation of the isolated (S)-enantiomer with formation of the (R) enantiomer.
•: Enantioselectivity and enantiomerization during the biodegradation were confirmed by exact mass spectrometry.

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