Centroacinar cells: At the center of pancreas regeneration

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Centroacinar cells: At the center of pancreas regeneration

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作者：Rebecca L. Beer^a ; ^{rbeer2@jhmi.edu" class="auth_mail" title="E-mail the corresponding author} ; Michael J. Parsons^a ; ^b ; Meritxell Rovira^c ; ^{merovira@clinic.ub.es" class="auth_mail" title="E-mail the corresponding author}
关键词：Centroacinar cell ; β cell ; Pancreas ; Regeneration ; Progenitor ; Zebrafish
刊名：Developmental Biology
出版年：2016
出版时间：1 May 2016
年：2016
卷：413
期：1
页码：8-15
全文大小：6880 K

文摘

• Centroacinar cells (CACs), specialized pancreatic ductal cells, are defined.

• CACs are endocrine progenitors during zebrafish development and regeneration.

• Whether CACs or other ductal cells are progenitors in adult mammals is discussed.

• Understanding CACs during pancreas regeneration can inform methods to treat disease.

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