Conditioned medium of olfactory ensheathing cells promotes the functional recovery and axonal regeneration after contusive spinal cord injury

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Conditioned medium of olfactory ensheathing cells promotes the functional recovery and axonal regeneration after contusive spinal cord injury

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作者：Mengchao Gu^a ; Zhengchao Gao^a ; Xiaohui Li^b ; Lei Guo^a ; Teng Lu^a ; Yuhuan Li^a ; Xijing He^a ; ^{xijing_h@vip.tom.com" class="auth_mail" title="E-mail the corresponding author}
关键词：Olfactory ensheathing cells (OECs) ; Conditioned medium ; Spinal cord injury (SCI) ; Axonal regeneration ; Diffusion tensor imaging (DTI)
刊名：Brain Research
出版年：2017
出版时间：1 January 2017
年：2017
卷：1654
期：part_PA
页码：43-54
全文大小：3331 K

文摘

•: We present a novel cell-free OEC based cell therapy to treat contusive SCI.
•: OEC-M treatment promotes functional recovery and axonal regeneration after SCI.
•: DTI is applied as a novel method to assess the axonal regeneration of spinal cord.
•: Conventional MRI and DTT are applied to visualize the repair process after SCI.
•: NF200 staining confirms the axonal regeneration around the injury epicenter.

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