KCNE1 and KCNE3: The yin and yang of voltage-gated K<sup>+</sup> channel regulation

网站地图 | English | 公务邮箱

About the library

Background
History
Leadership
Organization

Opening Hours
Collections
Help Via Email

Electronic Information Resources

KCNE1 and KCNE3: The yin and yang of voltage-gated K⁺ channel regulation

详细信息查看全文

作者：Geoffrey W. Abbott ^{abbottg@uci.edu" class="auth_mail" title="E-mail the corresponding author}
关键词：AV block ; atrioventricular block ; BLAST ; basic local alignment search tool ; cAMP ; cyclic adenosine monophosphate ; Cav channel ; voltage-gated calcium channel ; CHO ; Chinese Hamster ovary ; di ; drug-induced ; ERRγ ; estrogen-related receptor γ ; EST ; expressed sequence tag ; fs ; frameshift ; HCN ; hyperpolarization-activated ; cyclic nucleotide-gated ; HEK ; human embryonic kidney ; IKs/IsK ; slowly activating K+ current ; JLNS ; Jervell and Lange&ndash ; Nielsen syndrome ; KChIP ; K+ channel interacting protein ; Kv
刊名：Gene
出版年：2016
出版时间：15 January 2016
年：2016
卷：576
期：1
页码：1-13
全文大小：1086 K

文摘

•: KCNE1 and KCNE3 regulate K⁺ channel gating, voltage dependence and trafficking
•: KCNE1 and 3 often have opposite effects on channel function, especially so for KCNQ1
•: KCNE1-KCNQ1 channels are best known for their role in cardiomyocyte repolarization
•: KCNE3-KCNQ1 channels are important in various secretory epithelia
•: Human KCNE1 and KCNE3 sequence variants cause various cardiac arrhythmias

NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via email.