Core-shell LC-MS/MS method for quantification of second generation anticoagulant rodenticides diastereoisomers in rat liver in relationship with exposure of wild rats

详细信息    查看全文

• 作者：Isabelle Fourel ; ^{isabelle.fourel@vetagro-sup.fr} ; Marlè ; ne Damin-Pernik ; Etienne Benoit ; Virginie Lattard
• 关键词：Anticoagulant rodenticides ; Diastereoisomers separation ; Core-shell LC&ndash ; MS/MS ; Multi-residue validation ; Rat liver
• 刊名：Journal of Chromatography B
• 出版年：2017
• 出版时间：15 January 2017
• 年：2017
• 卷：1041-1042
• 期：Complete
• 页码：120-132
• 全文大小：3753 K
• 卷排序：1041

文摘

LC–MS/MS quantitative multi-residue method is fully validated to measure rodenticides. This method separates five pairs of diastereoisomers with a core-shell column. This method is a tool to explore diastereoisomers persistence in wildlife samples. Monitoring diastereoisomeric ratios from baits absorption to wildlife samples. Diastereoisomers ratios in liver of wild rats and rodenticides baits are different.