MicroRNA-155 is upregulated in MLL-rearranged AML but its absence does not affect leukemia development

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MicroRNA-155 is upregulated in MLL-rearranged AML but its absence does not affect leukemia development

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作者：Edith Schneider^a ; Anna Staffas^b ; ^c ; Linda Rö ; hner^a ; Kathrin Krowiorz^a ; Michael Heuser^d ; Konstanze Dö ; hner^a ; Lars Bullinger^a ; Hartmut Dö ; hner^a ; Linda Fogelstrand^b ; ^c ; Arefeh Rouhi^a ; Florian Kuchenbauer^a ; ^{florian.kuchenbauer@uni-ulm.de" class="auth_mail" title="E-mail the corresponding author} ; Lars Palmqvist^b ; ^c ; ^{lars.palmqvist@clinchem.gu.se" class="auth_mail" title="E-mail the corresponding author}
刊名：Experimental Hematology
出版年：2016
出版时间：December 2016
年：2016
卷：44
期：12
页码：1166-1171
全文大小：1178 K

文摘

•: MiR-155 expression is positively correlated with Meis1 expression levels in MLL-fusion acute myeloid leukemias.
•: Absence of miR-155 has no effect on the formation and progression of leukemia.
•: Depletion of miR-155 has no impact on MLL-fusion leukemia cell lines.

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