Physicochemical, antioxidant and biocompatible properties of chondroitin sulphate isolated from chicken keel bone for potential biomedical applications

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• 作者：Aruna Rani ; Rwivoo Baruah ; Arun Goyal ; ^{arungoyl@iitg.ernet.in}
• 关键词：GAG ; glycosaminoglycan ; GalNAc ; N-acetyl galactosamine ; GlcA ; D-glucuronic acid ; CS ; chondroitin sulphate ; DS ; dermatan sulphate ; C4S ; chondroitin 4-sulphate ; C6S ; chondroitin 6-sulphate ; DPPH ; 1-diphenyl-2-picrylhydrazyl ; MTT ; [3-(4 ; 5-dimethylthiazol-2-yl)-2 ; 5-diphenyltetrazolium bromide ; NMR ; nuclear magnetic resonance ; DLS ; dynamic light scattering ; DSC ; differential scanning calorimetery ; TGA ; thermogravimetric analysis
• 刊名：Carbohydrate Polymers
• 出版年：2017
• 出版时间：1 March 2017
• 年：2017
• 卷：159
• 期：Complete
• 页码：11-19
• 全文大小：1920 K
• 卷排序：159

文摘

CS-keel was isolated from chicken keel bone cartilage. Surface analysis of CS-keel showed the layered structure with regular depressions. CS-keel showed thermostability with a Td of 243 °C. MTT assay and microscopic observations revealed biocompatibility of CS-keel. CS-keel showed strong antioxidant and emulsifying properties.