Germ Cell-less Promotes Centrosome Segregation to Induce Germ Cell Formation

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• 作者：Dorothy A. Lerit¹ ; ⁷ ; ^{dlerit@emory.edu} ; Conrad W. Shebelut² ; Kristen J. Lawlor³ ; Nasser M. Rusan⁴ ; Elizabeth R. Gavis⁵ ; Paul Schedl⁵ ; ⁶ ; Girish Deshpande⁵ ; ^{gdeshpan@princeton.edu}
• 关键词：cell fate ; germ cells ; centrosome ; germ plasm ; germ cell-less ; stem cells
• 刊名：Cell Reports
• 出版年：2017
• 出版时间：24 January 2017
• 年：2017
• 卷：18
• 期：4
• 页码：831-839
• 全文大小：3700 K
• 卷排序：18

文摘

Germ cell-less (Gcl) promotes germline fate determinant segregation into germ cells Gcl mediates efficient centrosome separation dynamics Centrosome positioning instructs germ cell precocious cellularization