HLA-B27 subtypes in mulattoes and mestizos patients with spondyloartrhopathies.
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文摘
The object of this study was to investigate the distribution of HLA-B27 subtypes in patients with seronegative spondiloartrhopathies belonging to two ethnic groups of Colombia. PCR-SSOs was used to detect the polymorphism in exons 2 and 3 of HLA-B27 in two groups of patients: 44 mulattoes and 27 mestizos. Fifty-seven of them suffered of ankylosing spondylitis (AS), eight of Reiter syndrome (RS); four of reactive arthritis (reA) and two had ankylosing spondylitis plus anterior uveitis (UA).
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