Role of glyoxalase I gene polymorphisms in late-onset epilepsy and drug-resistant epilepsy

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Role of glyoxalase I gene polymorphisms in late-onset epilepsy and drug-resistant epilepsy

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作者：Hua Tao^a ; ¹ ; Ligang Si^b ; ¹ ; Xu Zhou^c ; ¹ ; Zhou Liu^d ; Zhonghua MA^e ; Haihong Zhou^a ; Wangtao Zhong^a ; Lili Cui^d ; Shuyan Zhang^f ; You Li^d ; Guoda Ma^d ; Jianghao Zhao^a ; Wenhui Huang^d ; Lifen Yao^b ; Zhien Xu^a ; Bin Zhao^a ; ^d ; ^{binzhaoe@163.com" class="auth_mail" title="E-mail the corresponding author} ; Keshen Li^d ; ^{likeshen1971@126.com" class="auth_mail" title="E-mail the corresponding author}
关键词：Glyoxalase I ; Single nucleotide polymorphisms ; Late-onset epilepsy ; Drug-resistant epilepsy
刊名：Journal of the Neurological Sciences
出版年：2016
出版时间：15 April 2016
年：2016
卷：363
期：Complete
页码：200-206
全文大小：246 K

文摘

•: The rs1049346 CC genotype plays a protective role against late-onset epilepsy.
•: The rs1049346 CC genotype exerts a protective effect against DRE.
•: The presence of the TAC haplotype (rs1130534–rs4746–rs1049346) is a marker of predisposition to DRE.
•: The presence of the AAT haplotype (rs1130534–rs4746–rs1049346) is a marker of protection against DRE.

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