A benzothiazole-based fluorescent probe for selective detection of H₂S in living cells and mouse hippocampal tissues

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• 作者：Yi Liu ; ¹ ; ^{cbpeliuyinew@163.com} ; Yan Ding¹ ; Jie Huang ; Xiaofei Zhang ; Tongyong Fang ; Yuyun Zhang ; Xian Zheng ; Xia Yang
• 关键词：Hydrogen sulfide ; Probe ; Fluorescence ; Hippocampus
• 刊名：Dyes and Pigments
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：138
• 期：Complete
• 页码：112-118
• 全文大小：1321 K
• 卷排序：138

文摘

We designed and synthesized a benzothiazole-based fluorescent probe EPS-HS for selective detection of H2S. The probe EPS-HS showed good cell permeability and H2S could be detected within the cells. In situ visualization of H2S was performed on the hippocampal slices of normal mice with probe EPS-HS. The probe will be applied for better treatment of neurological deficits caused by damage to the hippocampus.