Dimethyl-β-cyclodextrin/salazosulfapyridine inclusion complex-loaded chitosan nanoparticles for sustained release
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文摘

Job’s plot confirmed the 1:1 stoichiometry of the DMβCD/SASP inclusion complex.

FT-IR, NMR, PXRD, DSC, and SEM analysis confirmed the complex formation.

The DMβCD/SASP/CS NPs showed higher EE and LE than the SASP/CS NPs.

An obvious sustained-release manner of SASP was gained by the DMβCD/SASP/CS NPs.

The DMβCD/SASP/CS NPs exhibited lower toxic to LO2 cells than free SASP.

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