Global gene expression changes in the prefrontal cortex of rabbits with hypercholesterolemia and/or hypertension

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Global gene expression changes in the prefrontal cortex of rabbits with hypercholesterolemia and/or hypertension

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作者：Sau-Yeen Loke^a ; Peter Tsun-Hon Wong^b ; Wei-Yi Ong^a ; ^c ; ^{wei_yi_ong@nuhs.edu.sg}
关键词：Cholesterol ; Hypertension ; Proteasome ; Insulin ; Histone ; Inflammation
刊名：Neurochemistry International
出版年：2017
出版时间：January 2017
年：2017
卷：102
期：Complete
页码：33-56
全文大小：5395 K
卷排序：102

文摘

The prefrontal cortices of hypercholesterolemic rabbits were analyzed by microarray. Networks include proteasome, histone, insulin and cell signaling pathways. Increased amyloid beta peptide was found on cortical neurons.