Comparative analysis of two thioredoxin-like genes in black rockfish Sebastes schlegelii and their possible involvement in redox homeostasis and innate immune responses

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• 作者：Roopasingam Kugapreethan^a ; ^b ; Navaneethaiyer Umasuthan^a ; ^c ; Qiang Wan^a ; ^b ; William Shanthakumar Thulasitha^a ; ^b ; Chul Kim^d ; ^{chulnice@kiom.re.kr} ; Jehee Lee^a ; ^b ; ^{jehee@jejunu.ac.kr}
• 关键词：Thioredoxin (TXN) ; Reactive oxygen species (ROS) ; Black rockfish ; Antioxidant ; Radical scavenging activity
• 刊名：Developmental & Comparative Immunology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：67
• 期：Complete
• 页码：43-56
• 全文大小：4757 K
• 卷排序：67

文摘

Genes involve in redox homeostasis are studied in black rockfish (Sebastes schlegelii). Transcriptional modulations of SsTXN-like 1 and SsMtTXN-like are monitored against the various immune stimulants. The free radical scavenging activities of SsTXN-like 1 and SsMtTXN-like are assessed by ESR spectroscopy. SsTXN-like 1 and SsMtTXN-like could act as potential antioxidant systems in black rockfish.