Knockdown of Dynamitin in testes significantly decreased male fertility in Drosophila melanogaster

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• 作者：Chun-Hong Wu^a ; Qiong Zong^a ; An-Li Du^a ; Wei Zhang^a ; Han-Chao Yao^a ; Xiao-Qiang Yu^a ; ^b ; Yu-Feng Wang^a ; ^{yfengw@mail.ccnu.edu.cn}
• 关键词：Dynamitin ; Drosophila melanogaster ; Spermiogenesis ; Mitochondria ; Individualization complex ; Male fertility
• 刊名：Developmental Biology
• 出版年：2016
• 出版时间：1 December 2016
• 年：2016
• 卷：420
• 期：1
• 页码：79-89
• 全文大小：1663 K
• 卷排序：420

文摘

Dmn indeed functions in inducing male fertility defect following Wolbachia infection. Dmn-knockdown testes undergo abnormal spermiogenesis. Knockdown of Dmn decreased abundance of dynein and tubulin in the spermatids. Knockdown of Dmn reduced output of sperm. Knockdown of Dmn might damage transport ability for many important cellular contents.