Conserved Intramolecular Interactions Maintain Myosin Interacting-Heads Motifs Explaining Tarantula Muscle Super-Relaxed State Structural Basis

网站地图 | English | 公务邮箱

About the library

Background
History
Leadership
Organization

Opening Hours
Collections
Help Via Email

Electronic Information Resources

Conserved Intramolecular Interactions Maintain Myosin Interacting-Heads Motifs Explaining Tarantula Muscle Super-Relaxed State Structural Basis

详细信息查看全文

作者：Lorenzo Alamo¹ ; ^{lorenzo.alamo@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Dan Qi² ; ^{isaacruby@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Willy Wriggers³ ; ^{wwrigger@odu.edu" class="auth_mail" title="E-mail the corresponding author} ; Antonio Pinto¹ ; ^{pinto.misle@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Jingui Zhu² ; ^{osmanthusz@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Aivett Bilbao¹ ; ^&dagger ; ; ^{aivettbilbao@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Richard E. Gillilan⁴ ; ^{reg8@cornell.edu" class="auth_mail" title="E-mail the corresponding author} ; Songnian Hu² ; ^{husn@big.ac.cn" class="auth_mail" title="E-mail the corresponding author} ; Raú ; l Padró ; n¹ ; ^{raul.padron@gmail.com" class="auth_mail" title="E-mail the corresponding author}
关键词：BH ; blocked head ; C loop ; cardiac loop ; CM loop ; cardiomyopathy loop ; ELC ; essential light chain ; FH ; free head ; HMM ; heavy meromyosin ; IHM ; interacting-heads motif ; MHC ; myosin II heavy chain ; NTE ; N-terminal extension ; RLC ; regulatory light chain ; S2 ; subfragment 2 ; SAXS ; small angle X-ray solution scattering ; SRX ; super-relaxed state
刊名：Journal of Molecular Biology
出版年：2016
出版时间：27 March 2016
年：2016
卷：428
期：6
页码：1142-1164
全文大小：3491 K

文摘

•: An atomic model of two heavy meromyosin IHMs is achieved.
•: Conserved intramolecular interactions suggests IHM presence across animal species.
•: These interactions and IHM model explains the structural origin of super-relaxation.
•: The super-relaxed state should also be conserved across animal species.

NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via email.