Reactions of 3-isochromanone with aromatic aldehydes—microwave assisted condensations performed on solid basic inorganic supports

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• 作者：Andrá ; s Vass ; Andrá ; s Fö ; ldesi and Tamá ; s Ló ; rá ; nd
• 关键词：Isochromane ; Knoevenagel condensation ; Microwave ; Validation ; TLC
• 刊名：Journal of Biochemical and Biophysical Methods
• 出版年：2006
• 出版时间：30 November 2006
• 年：2006
• 卷：69
• 期：1-2
• 页码：179-187
• 全文大小：123 K

文摘

An improved Knoevenagel condensation of 3-isochromanone and aromatic aldehydes can be achieved by microwave irradiation on solid supports in the presence of various catalysts. This synthetic method offers some major advantages, especially the possibility to change the ratio of E/Z isomers.