Randomized Double-Blind Study of the Safety and Immunogenicity of Standard-Dose Trivalent Inactivated Influenza Vaccine versus High-Dose Trivalent Inactivated Influenza Vaccine in Adult Hematopoietic Stem Cell Transplantation Patients

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Randomized Double-Blind Study of the Safety and Immunogenicity of Standard-Dose Trivalent Inactivated Influenza Vaccine versus High-Dose Trivalent Inactivated Influenza Vaccine in Adult Hematopoietic Stem Cell Transplantation Patients

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作者：Natasha B. Halasa¹ ; ^{natasha.halasa@vanderbilt.edu" class="auth_mail" title="E-mail the corresponding author} ; Bipin N. Savani² ; Ishan Asokan³ ; Adetola Kassim² ; Rhea Simons² ; Chelsey Summers² ; John Bourgeois² ; Carey Clifton² ; Leigh Ann Vaughan² ; Catherine Lucid² ; Li Wang⁴ ; Christopher Fonnesbeck⁴ ; Madan Jagasia²
关键词：Influenza ; Vaccination ; Hematopoietic stem cell transplantation
刊名：Biology of Blood and Marrow Transplantation
出版年：2016
出版时间：March 2016
年：2016
卷：22
期：3
页码：528-535
全文大小：534 K

文摘

•: High-dose trivalent inactivated influenza vaccine was found to be safe and well tolerated in adult hematopoietic stem cell transplant recipients
•: The high-dose group had a higher percentage of individuals with titers ≥ 1:40 for the H3N2 strain
•: The high-dose group also had a higher geometric mean titer against the H3N2 strain