Fe65 negatively regulates Jagged1 signaling by decreasing Jagged1 protein stability through the E3 ligase Neuralized-like 1

网站地图 | English | 公务邮箱

About the library

Background
History
Leadership
Organization

Opening Hours
Collections
Help Via Email

Electronic Information Resources

Fe65 negatively regulates Jagged1 signaling by decreasing Jagged1 protein stability through the E3 ligase Neuralized-like 1

详细信息查看全文

作者：Hye-Jin Lee^a ; Ji-Hye Yoon^a ; Ji-Seon Ahn^a ; Eun-Hye Jo^a ; Mi-Yeon Kim^a ; Young Chul Lee^a ; Jin Woo Kim^b ; Eun-Jung Ann^a ; ^{eunjung36@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Hee-Sae Park^a ; ^{proteome@jnu.ac.kr" class="auth_mail" title="E-mail the corresponding author}
关键词：AP1 ; Activator Protein 1 ; JICD ; Jagged1 intracellular domain ; Notch1-IC ; Notch1 intracellular domain ; Neurl1 ; Neuralized-like 1
刊名：Biochimica et Biophysica Acta (BBA)-Molecular Cell Research
出版年：2015
出版时间：November 2015
年：2015
卷：1853
期：11
页码：2918-2928
全文大小：1472 K

文摘

•: Fe65 inhibits AP1-mediated JICD transactivation in a Tip60-independent manner.
•: Fe65 induces the Jagged1 degradation by both proteasomal and lysosomal proteolysis.
•: Fe65 interacts with Jagged1 and JICD.
•: Fe65 promotes the interaction between Jagged1 and E3 ligase Neurl1.

NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via email.