Short- and long-term dopamine depletion causes enhanced beta oscillations in the cortico-basal ganglia loop of parkinsonian rats

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Short- and long-term dopamine depletion causes enhanced beta oscillations in the cortico-basal ganglia loop of parkinsonian rats

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作者：Maximilian H. Beck ; Jens K. Haumesser ; Johanna Kü ; hn ; Jennifer Altschü ; ler ; Andrea A. Kü ; hn ; Christoph van Riesen ; ^{christoph.van-riesen@charite.de" class="auth_mail" title="E-mail the corresponding author}
关键词：Parkinson's disease ; 6-OHDA ; Reserpine ; Beta oscillations ; Gamma oscillations ; Cortico-basal ganglia loop
刊名：Experimental Neurology
出版年：2016
出版时间：December 2016
年：2016
卷：286
期：Complete
页码：124-136
全文大小：1635 K

文摘

•: Enhanced beta power was found in the basal ganglia of both PD models.
•: An increase in cortical beta power can be only found in the chronic 6-OHDA model.
•: Beta peak frequencies differ profoundly between the models in the basal ganglia.
•: Our data support the theory of a relation between beta oscillations and akinesia.
•: Our study questions the motor cortex as a generator of beta oscillations in PD.

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