Study of stiffness effects of poly(amidoamine)-poly(n-isopropyl acrylamide) hydrogel on wound healing

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Study of stiffness effects of poly(amidoamine)-poly(n-isopropyl acrylamide) hydrogel on wound healing

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作者：Shixuan Chen^a ; ^c ; ¹ ; Junbin Shi^c ; ¹ ; Xiaolin Xu^a ; Jianyang Ding^a ; Wen Zhong^d ; Lu Zhang^b ; ^{zlulu70@126.com" class="auth_mail" title="E-mail the corresponding author} ; Malcolm Xing^c ; ^{malcolm.xing@umanitoba.ca" class="auth_mail" title="E-mail the corresponding author} ; Lin Zhang^a ; ^e ; ^{zlilyzh@126.com" class="auth_mail" title="E-mail the corresponding author}
关键词：Skin wound healing ; Poly(amidoamine) ; P(N-isopropylacrylamide) ; Hydrogel ; Stiffness
刊名：Colloids and Surfaces B: Biointerfaces
出版年：2016
出版时间：1 April 2016
年：2016
卷：140
期：Complete
页码：574-582
全文大小：4675 K

文摘

•: Stiffness tunable hydrogel of poly(amidoamine)–poly(N-isopropylacrylamide).
•: Hydrogel stiffness influencing wound contraction.
•: Hydrogel stiffness deciding keratinocytes proliferation.
•: Hydrogel stiffness regulating collagen I deposit.
•: Hydrogel stiffness regulating growth factor secretion of TGF-β1 and bFGF.
•: Hydrogel stiffness affecting scar formation.

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