Clinical use of Hypericum perforatum (St John's wort) in depression: A meta-analysis

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• 作者：Qin Xiang Ng^a ; ^{ng.qin.xiang@u.nus.edu} ; Nandini Venkatanarayanan^b ; Collin Yih Xian Ho^c
• 关键词：Depression ; Complementary and alternative medicine ; St John's wort ; Hypericin ; Hyperforin ; Antidepressant
• 刊名：Journal of Affective Disorders
• 出版年：2017
• 出版时间：1 March 2017
• 年：2017
• 卷：210
• 期：Complete
• 页码：211-221
• 全文大小：1646 K
• 卷排序：210

文摘

This is the most up-to-date, large-scale meta-analysis of St John’s wort. Studies published in English, German and Chinese were examined. 27 clinical trials with a total of 3808 patients were reviewed. St John’s wort had comparable efficacy as SSRIs for mild-moderate depression. Lower discontinuation or dropout rate as compared to SSRIs.