The effect of aggregation into fractals or microgels on the charge density and the isoionic point of globular proteins
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The isoionic point of β-lactoglobulin is at pH 5.0 and IIP = 4.9 for WPI.

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The pH shifts towards the IIP at higher salt or protein concentration.

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After aggregation the pH depends more strongly on the charge density.

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The dependence is stronger for microgels than for fractals.

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The dependence is independent of the aggregate size.

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