Hypocretin/orexin loss changes the hypothalamic immune response
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文摘

LPS induced-hypothalamic immune response was altered by hypocretin loss.

Hypocretin expression was completely abolished by LPS in hypocretin/ataxin-3 mice.

An increase in HDC cells and Hdc was found in hypocretin/ataxin-3 mice.

Hypocretin loss did impact the change in Ifng and Csf3.

c-Fos-positive/HDC cells in hypocretin/ataxin-3 mice was elevated by LPS.

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