Luteal function in mares following administration of oxytocin, cloprostenol or saline on Day 0, 1 or 2 post-ovulation
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文摘
Mares (n=30) were treated in the post-ovulatory period with saline, oxytocin, or cloprostenol (Clo). Dose, administration frequency and treatment day (Day 0, 1 or 2 post-ovulation) were evaluated. Interovulatory interval of control cycles was 22.7 (±0.36) days with a range of 20.6 (±1.44) to 23.8 (±1.39) days among all treatment groups. Mares treated with two micro-doses of cloprostenol on Day 2 post-ovulation had the shortest interovulatory interval. This group also had the lowest mean circulating progesterone concentrations on Days 3–7 and 13, and was the slowest group to reach concentrations of 5ng/ml. Repeated administration of cloprostenol over 24h in the early post-ovulatory period may more effectively impair luteal function than single doses. This could negatively affect pregnancy outcome but may be effective for lysing the early post-ovulatory luteal structure when mares are not bred.
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