Metal free amination of 2-chloroazoles in aqueous medium

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• 作者：R. Uday Kumar ; K. Harsha Vardhan Reddy ; ^{drharshaindia@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; B.S.P. Anil Kumar ; G. Satish ; V. Prakash Reddy ; Y.V.D. Nageswar ; ^{dryvdnageswar@gmail.com" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Copper on chitosan ; Recyclability ; Boronic acids ; 1 ; 2 ; 3-Triazoles ; Click reaction
• 刊名：Tetrahedron Letters
• 出版年：2016
• 出版时间：10 February 2016
• 年：2016
• 卷：57
• 期：6
• 页码：637-640
• 全文大小：526 K

文摘

A green approach for the synthesis of 2-amino azoles by the reaction of 2-chloro azoles with various types of amines using water as an environment friendly solvent at room temperature has been developed. The significant features of this methodology are short reaction time and easy product separation. This approach provides various biologically active compounds in good to excellent yields without adding any catalyst, ligand, or base.