刊名:Biochemical and Biophysical Research Communications
出版年:2016
出版时间:2 September 2016
年:2016
卷:477
期:4
页码:1078-1084
全文大小:2103 K
文摘
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Tspan7 expression is up-regulated during osteoclastogenesis.
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Tspan7 regulates podosome belt organization in osteoclasts.
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Tspan7 is crucial for sealing zone formation and bone-resorption by osteoclasts.
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Src and Pyk2 phosphorylation and microtubule acetylation mediate Tspan7 function.
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