Induced neural stem cells from distinct genetic backgrounds exhibit different reprogramming status

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Induced neural stem cells from distinct genetic backgrounds exhibit different reprogramming status

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作者：Sung Min Kim^a ; ^b ; ¹ ; Kyung Tae Lim^a ; ¹ ; Tae Hwan Kwak^a ; ¹ ; Seung Chan Lee^a ; Jung Hyun Im^a ; Sai Hali^a ; Seon In Hwang^a ; Dajeong Kim^c ; Jeongho Hwang^b ; Kee-Pyo Kim^d ; Hak-Jae Chung^f ; Jeong Beom Kim^g ; Kinarm Ko^a ; ^h ; Hyung-Min Chung^a ; ^h ; Hoon Taek Lee^b ; Hans R. Schö ; ler^d ; ^e ; Dong Wook Han^a ; ^h ; ^{dwhan@konkuk.ac.kr" class="auth_mail" title="E-mail the corresponding author}
关键词：iNSCs ; induced neural stem cells ; iPSCs ; induced pluripotent stem cells ; iEpiSCs ; induced epiblast stem cells ; MEFs ; mouse embryonic fibroblasts ; qPCR ; quantitative polymerase chain reaction ; cNSCs ; control neural stem cells
刊名：Stem Cell Research
出版年：2016
出版时间：March 2016
年：2016
卷：16
期：2
页码：460-468
全文大小：2218 K

文摘

•: The iNSCs from different mouse strains showed the distinct conversion efficiency.
•: The genetic background influenced the clonal expansion of iNSCs.
•: The transcriptional reprogramming status was influenced by genetic backgrounds.
•: The genetic background affected the in vitro differentiation potential of iNSCs.

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