Effect of fish oil on lateral mobility of prostaglandin F_2α (FP) receptors and spatial distribution of lipid microdomains in bovine luteal cell plasma membrane in vitro

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• 作者：M.R. Plewes^a ; P.D. Burns^a ; ^{Patrick.burns@unco.edu} ; P.E. Graham^a ; R.M. Hyslop^b ; B.G. Barisas^c
• 关键词：Microdomain ; Fish oil ; Prostaglandin F2α FP receptor ; Single particle tracking ; Corpus luteum
• 刊名：Domestic Animal Endocrinology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：58
• 期：Complete
• 页码：39-52
• 全文大小：1977 K
• 卷排序：58

文摘

Fish oil disrupts spatial distribution of lipid microdomains in dose-dependent manner.Demonstrated successful labeling of prostaglandin F2α receptor for single particle tracking.Fish oil increases the lateral mobility of unbound FP receptor.Ligand did not influence lateral mobility of fish oil–treated FP receptor.