We examined the association between pesticide exposure and ESRD among farm wives.
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Among all wives, overall use of pesticides was inversely associated with ESRD risk.
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Among pesticide-applying wives, cumulative pesticide use was associated with ESRD.
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Husband's use of paraquat and butylate was positively associated with ESRD in wives.
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ESRD rate increased with husband's increasing cumulative use of these pesticides.
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