Monitoring γ-glutamyl transpeptidase activity and evaluating its inhibitors by a water-soluble near-infrared fluorescent probe

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Monitoring γ-glutamyl transpeptidase activity and evaluating its inhibitors by a water-soluble near-infrared fluorescent probe

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作者：Lihong Li ; Wen Shi ; ^{shiwen@iccas.ac.cn" class="auth_mail" title="E-mail the corresponding author} ; Xiaofeng Wu ; Qiuyu Gong ; Xiaohua Li ; Huimin Ma
关键词：γ-Glutamyl transpeptidase ; Near-infrared fluorescent probe ; Water-soluble fluorescent probe ; Inhibitors
刊名：Biosensors and Bioelectronics
出版年：2016
出版时间：15 July 2016
年：2016
卷：81
期：Complete
页码：395-400
全文大小：684 K

文摘

•: The first near-infrared fluorescent probe is developed for γ-glutamyl transpeptidase.
•: The probe has an emission wavelength over 700 nm with high selectivity and sensitivity.
•: The probe exhibits excellent water-solubility.
•: The probe is used to image γ-glutamyl transpeptidase activity in zebrafish.

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