New phenolic compounds from the leaves of Artocarpus heterophyllus

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• 作者：Xiao-Ling Wang^a ; Xia-Xia Di^b ; Tao Shen^b ; Shu-Qi Wang^b ; Xiao-Ning Wang^b ; ^{wangxn@sdu.edu.cn}
• 关键词：Artocarpus heterophyllus ; 2-Arylbenzofuran ; Artocarstilbene B ; (E)-3 ; 5-Dihydroxy-4-(3-methylbut-1-enyl)benzaldehyde ; Cytotoxicity
• 刊名：Chinese Chemical Letters
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：28
• 期：1
• 页码：37-40
• 全文大小：315 K
• 卷排序：28

文摘

One new 2-arylbenzofuran derivative, artocarstilbene B (1), one new benzaldehyde derivative, (E)-3,5-dihydroxy-4-(3-methylbut-1-enyl)benzaldehyde (2), as well as 18 known compounds (3–20) were obtained from the leaves of Artocarpus heterophyllus. Their structures were elucidated on the basis of extensive spectroscopic techniques including 2D NMR and HR-ESIMS. Many compounds exhibited moderate to weak inhibitory activity against the proliferation of the PC-3, NCI-H460, and A549 cancer cell lines.