Upregulation of soluble B7-H3 in NSCLC-derived malignant pleural effusion: A potential diagnostic biomarker correlated with NSCLC staging

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Upregulation of soluble B7-H3 in NSCLC-derived malignant pleural effusion: A potential diagnostic biomarker correlated with NSCLC staging

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作者：Liwen Chen^a ; Guangbo Zhang^b ; Shouqin Sheng^c ; Qiang Zhou^a ; Ying Pan^a ; Shihe Guan^a ; ^{shiheguan@126.com" class="auth_mail" title="E-mail the corresponding author}
关键词：MPEs ; malignant pleural effusions ; NPEs ; nonneoplastic pleural effusions ; sB7-H3 ; soluble B7-H3 ; CEA ; carcino-embryonic antigen ; CYFRA21-1 ; Cytokeratin 19 fragment
刊名：Clinica Chimica Acta
出版年：2016
出版时间：1 June 2016
年：2016
卷：457
期：Complete
页码：81-85
全文大小：521 K

文摘

•: sB7-H3 is upregulated in NSCLC-derived malignant pleural effusions (MPEs).
•: Sera and cognate MPEs have comparable and closely correlated sB7-H3 expression.
•: MPEs-derived sB7-H3 has equal diagnostic effectiveness with CEA and CYFRA21-1.
•: MPEs-derived sB7-H3 is correlated with smoking status and TNM stage of NSCLC.

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