Alternative splicing in nicotinic acetylcholine receptor subunits from Locusta migratoria and its influence on acetylcholine potencies

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• 作者：Yixi Zhang ; Yang Liu ; Haibo Bao ; Huahua Sun ; Zewen Liu ; ^{liuzewen@njau.edu.cn}
• 关键词：Locusta migratoria ; Nicotinic acetylcholine receptors (nAChRs) ; Alternative splicing ; Agonist potency
• 刊名：Neuroscience Letters
• 出版年：2017
• 出版时间：18 January 2017
• 年：2017
• 卷：638
• 期：Complete
• 页码：151-155
• 全文大小：1589 K
• 卷排序：638

文摘

Alternative splicing was found in six nAChR α subunits from Locusta migratoria. Recombinant nAChRs were constructed with rat β2 and one of Locα1-5 or α8-9 subunits. Alternative splicing in three α subunits showed influences on acetylcholine potency.