Proteomic analysis of lysine succinylation of the human pathogen Histoplasma capsulatum

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• 作者：Longxiang Xie<sup>asup><sup> ; sup><sup>1sup> ; Juan Li<sup>bsup><sup> ; sup><sup>1sup> ; Wanyan Deng<sup>asup><sup> ; sup><sup>1sup> ; Zhaoxiao Yu<sup>asup> ; Wenjie Fang<sup>bsup> ; Min Chen<sup>bsup> ; Wanqing Liao<sup>bsup> ; Jianping Xie<sup>asup><sup> ; sup><sup>georgex@swu.edu.cnsup> ; Weihua Pan<sup>bsup><sup> ; sup><sup>panweihua@medmail.com.cnsup>
• 关键词：Post-translational protein modification ; Lysine succinylation ; Histone proteins ; Metabolism ; Chaperone
• 刊名：Journal of Proteomics
• 出版年：2017
• 出版时间：10 February 2017
• 年：2017
• 卷：154
• 期：Complete
• 页码：109-117
• 全文大小：1868 K
• 卷排序：154

文摘

Our data provides the first global survey of succinylation in Histoplasma capsulatum. More than 52% of the succinylated proteins are metabolic enzymes, which is consistent with previous reports. Thirteen lysine succinylation sites on histones were found in H. capsulatum.