Selective inhibition of MAO-A activity results in an antidepressant-like action of 2-benzoyl 4-iodoselenophene in mice

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• 作者：Daniela Velasquez ; Caroline Quines ; Renan Pistó ; ia ; Gilson Zeni ; Cristina W. Nogueira ; ^{criswn@ufsm.br}
• 关键词：Selenophenes ; Organoselenium ; Antidepressant-like action ; Na+ ;   ; K+ ATPase ; Monoamine oxidase
• 刊名：Physiology & Behavior
• 出版年：2017
• 出版时间：1 March 2017
• 年：2017
• 卷：170
• 期：Complete
• 页码：100-105
• 全文大小：546 K
• 卷排序：170

文摘

C17H11IOSe presents an antidepressant-like effect in mice. C17H11IOSe is a selective inhibitor of cerebral cortical MAO-A activity and interacts with the brain monoaminergic system. C17H11IOSe caused dose-dependent effects on Na+ K+ ATPase activity.