A bundle that includes active surveillance, contact precaution for carriers, and cefazolin-based antimicrobial prophylaxis prevents methicillin-resistant Staphylococcus aureus infections in clean orthopedic surgery
We implemented a prevention bundle for orthopedic MRSA SSIs.
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The bundle reinforced contact precaution and AMP stewardship.
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The MRSA SSI rate correlated negatively with cefazolin AUD.
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Prolonged AMP may increase the risk of MRSA SSI.
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The bundle was associated with the decrease in the incidence of MRSA SSI.
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