Medial and Lateral Entorhinal Cortex Differentially Excite Deep versus Superficial CA1 Pyramidal Neurons

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• 作者：Arjun V. Masurkar¹ ; ² ; ⁶ ; ⁷ ; ^{arjun.masurkar@nyumc.org} ; Kalyan V. Srinivas³ ; David H. Brann³ ; Richard Warren³ ; Daniel C. Lowes³ ; Steven A. Siegelbaum³ ; ⁴ ; ⁵
• 关键词：hippocampus ; CA1 ; lateral entorhinal cortex ; medial entorhinal cortex ; pyramidal neuron heterogeneity ; radial axis ; transverse axis ; perforant pathway ; Schaffer collateral ; spines
• 刊名：Cell Reports
• 出版年：2017
• 出版时间：3 January 2017
• 年：2017
• 卷：18
• 期：1
• 页码：148-160
• 全文大小：3143 K
• 卷排序：18

文摘

LEC inputs excite superficial versus deep CA1 pyramidal neurons toward subiculum MEC inputs excite deep versus superficial CA1 pyramidal neurons toward CA2 Differential EC excitation reflects differences in SLM dendrite spine number SC EPSPs and SR dendrite spine number are similar among deep and superficial neurons