Synthesis of diarylheptanoids, (5S)-5-acetoxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-3-heptanone and (3S,5S)-3,5-diacetoxy-1,7-bis(4-hydroxy-3-methoxyphenyl)heptane

详细信息    查看全文

• 作者：Gowravaram Sabitha^a ;   ; ^{gowravaramsr@yahoo.com} ; Gajangi Chandrashekhar^a ; Kurra Yadagiri^a ; Jhillu Singh Yadav^a ;   ; ^b
• 刊名：Tetrahedron: Asymmetry
• 出版年：2011
• 出版时间：15 October 2011
• 年：2011
• 卷：22
• 期：18-19
• 页码：1729-1735
• 全文大小：489 K

文摘

The total syntheses of the first examples of diarylheptanoid natural products (5S)-5-acetoxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-3-heptanone 1, and (3S,5S)-3,5-diacetoxy-1,7-bis(4-hydroxy-3-methoxyphenyl)heptane 2 isolated from the rhizomes of Zingiber officinale were accomplished using Sharpless epoxidation and cross-metathesis reactions as the key steps.