The emerging epitranscriptomics of long noncoding RNAs

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The emerging epitranscriptomics of long noncoding RNAs

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作者：Andrew Shafik^a ; ¹ ; ^{andrew.shafik@anu.edu.au" class="auth_mail" title="E-mail the corresponding author} ; Ulrike Schumann^a ; ¹ ; ^{ulrike.schumann@anu.edu.au" class="auth_mail" title="E-mail the corresponding author} ; Maurits Evers^a ; ^{maurits.evers@anu.edu.au" class="auth_mail" title="E-mail the corresponding author} ; Tennille Sibbritt^a ; ² ; ^{t.sibbritt@garvan.org.au" class="auth_mail" title="E-mail the corresponding author} ; Thomas Preiss^a ; ^b ; ³ ; ^{thomas.preiss@anu.edu.au" class="auth_mail" title="E-mail the corresponding author}
关键词：m5C ; 5-methylcytidine ; hm5C ; 5-hydroxymethylcytidine ; m6A ; N6-methyladenosine ; Ψ ; pseudouridine ; NGS ; next generation sequencing ; bsRNA-seq ; bisulfite RNA sequencing ; Aza-IP ; 5-azacytidine RNA immunoprecipitation ; iCLIP ; individual-nucleotide-resolution crosslinking and immunoprecipitation ; miCLIP ; methylation individual-nucleotide-resolution crosslinking and immunoprecipitation
刊名：Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
出版年：2016
出版时间：January 2016
年：2016
卷：1859
期：1
页码：59-70
全文大小：1108 K

文摘

•: 5">RNA modifications are chemically diverse and implement epitranscriptomic regulation.
•: Technological advances in next generation sequencing have propelled the transcriptome-wide mapping of RNA modifications.
•: 5">Emerging information on the role of post-transcriptional modifications in long noncoding RNA function is reviewed here

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