The Value of Certification in HIV/AIDS Nursing

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• 作者：Michael Relf ; Barbara Berger ; Michele Crespo-Fierro ; R. Kevin Mallinson ; Cass ; ra Miller-Hardwick
• 关键词：HIV/AIDS ; risk behaviors ; late middle-aged ; older adults
• 刊名：Journal of the Association of Nurses in AIDS Care
• 出版年：2004
• 出版时间：January-February 2004
• 年：2004
• 卷：15
• 期：1
• 页码：60-64
• 全文大小：62 K

文摘

DNA-based fluorescent microarrays (sometimes called “biochips”) are fast becoming the preferred tool for studying a variety of complex biochemical phenomena ranging from multiplex mutation detection, to gene mapping and expression monitoring, to high throughput screening for new drug candidates. Fluorescence is a low energy phenomenon. The need for rapid, high resolution, wide field imaging of fluorescent microarrays calls for a specialized microscope architecture. We now describe the design of a “Flying Objective” epi-fluorescence microscope that is ideally suited to this application, and compare the performance of this novel instrument with two other commercial epi-fluorescence microscopes designed to read DNA microarrays.