Familial idiopathic normal pressure hydrocephalus

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Familial idiopathic normal pressure hydrocephalus

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作者：Joel Huovinen^a ; ^{joel_huovinen@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Sami Kastinen^a ; ^{samikas@student.uef.fi" class="auth_mail" title="E-mail the corresponding author} ; Simo Komulainen^a ; ^{simokom@student.uef.fi" class="auth_mail" title="E-mail the corresponding author} ; Minna Oinas^b ; ^{minna.oinas@hus.fi" class="auth_mail" title="E-mail the corresponding author} ; Cecilia Avellan^b ; ^{cecilia.avellan@hus.fi" class="auth_mail" title="E-mail the corresponding author} ; Janek Frantzen^c ; ^{janek.frantzen@tyks.fi" class="auth_mail" title="E-mail the corresponding author} ; Jaakko Rinne^c ; ^{jaakko.rinne@tyks.fi" class="auth_mail" title="E-mail the corresponding author} ; Antti Ronkainen^d ; ^{antti.ronkainen@pshp.fi" class="auth_mail" title="E-mail the corresponding author} ; Mikko Kauppinen^e ; ^{mikko.kauppinen@ppshp.fi" class="auth_mail" title="E-mail the corresponding author} ; Kimmo Lö ; nnrot^f ; ^{kimmo.lonnrot@epshp.fi" class="auth_mail" title="E-mail the corresponding author} ; Markus Perola^g ; ^h ; ^{markus.perola@thl.fi" class="auth_mail" title="E-mail the corresponding author} ; Okko T. Pyykkö ; ^a ; ^{okko.pyykko@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Anne M. Koivistoⁱ ; ^{anne.koivisto@kuh.fi" class="auth_mail" title="E-mail the corresponding author} ; Anne M. Remesⁱ ; ^{anne.remes@uef.fi" class="auth_mail" title="E-mail the corresponding author} ; Hilkka Soininenⁱ ; ^{hilkka.soininen@uef.fi" class="auth_mail" title="E-mail the corresponding author} ; Mikko Hiltunenⁱ ; ^j ; ^{mikko.hiltunen@uef.fi" class="auth_mail" title="E-mail the corresponding author} ; Seppo Helisalmiⁱ ; ^{seppo.helisalmi@uef.fi" class="auth_mail" title="E-mail the corresponding author} ; Mitja Kurki^a ; ^k ; ^l ; ^m ; ^{mitja.kurki@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Juha E. Jä ; ä ; skelä ; inen^a ; ^{juha.e.jaaskelainen@kuh.fi" class="auth_mail" title="E-mail the corresponding author} ; Ville Leinonen^a ; ^{ville.leinonen@kuh.fi" class="auth_mail" title="E-mail the corresponding author}
关键词：Normal pressure hydrocephalus ; Idiopathic ; Alzheimer's disease ; APOE ; Pedigree ; Genetics ; Familial aggregation ; Heritability ; Complex traits
刊名：Journal of the Neurological Sciences
出版年：2016
出版时间：15 September 2016
年：2016
卷：368
期：Complete
页码：11-18
全文大小：970 K

文摘

•: Familial subgroup of iNPH is introduced and characterized.
•: 5% of iNPH-patients had shunt-operated relative(s).
•: Risk of dementia may be increased in familial iNPH.

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