Microwave-assisted synthesis, structure and anti-tumor activity of selenized Artemisia sphaerocephala polysaccharide

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• 作者：Junlong Wang^a ; ^b ; ^{nuno-vai@163.com} ; Xiaoping Yang^a ; ^{13060729@qq.com} ; Aijuan Bao^a ; ^{wyq127127@163.com} ; Xinlong Liu^a ; ^{xlliu@163.com} ; Junyuan Zeng^a ; ^{1622081261@qq.com} ; Xiurong Liu^a ; ^{xrliu@sina.com} ; Jian Yao^a ; ^b ; ^{yaojiani@nwnu.edu.cn} ; Ji Zhang^a ; ^b ; ^c ; ^{nuno-vai@hotmail.com.cn} ; Ziqiang Lei^c ; ^{leiziq@nwnu.edu.cn}
• 关键词：ASP ; Artemisia sphaerocephala polysaccharide ; SeASP ; Selenized Artemisia sphaerocephala polysaccharide ; SEC-MALLS ; Size-exclusion chromatograph combined with multi-angle laser light scattering photometer ; AFM ; Atomic force microscopy ; SeASPMW ; Selenized ASP synthesized in microwave field ; FT-IR ; Fourier transform infrared spectroscopy ; H2SeO3 ; Selenious acid ; MW ; Weight average molecular mass ; CCK-8 ; Cell counting kit-8 ; PI ; Propidium iodides ; PBS ; Phosphate buffer saline ; df ; Fractal dimension
• 刊名：International Journal of Biological Macromolecules
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：95
• 期：Complete
• 页码：1108-1118
• 全文大小：3456 K
• 卷排序：95

文摘

Microwave assisted selenylation of Artemisia sphaerocephala polysaccharide was studied. The chemical structure and solution conformation were characterized. Se content had a major influence on anti-tumor activities in vitro.