Development of a new ARCHITECT automated periostin immunoassay

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• 作者：Nicolette M. Jeanblanc^a ; Philip M. Hemken^a ; Maria J. Datwyler^a ; Susan E. Brophy^a ; T. Scott Manetz^b ; Rozanne Lee^c ; Meina Liang^c ; Partha S. Chowdhury^d ; Reena Varkey^d ; Ethan P. Grant^e ; Katie Streicher^e ; Lydia Greenlees^e ; Koustubh Ranade^e ; Gerard J. Davis^a ; ^{gerard.davis@abbott.com}
• 关键词：BGG ; bovine gamma globulin ; CI ; confidence interval ; CLSI ; Clinical and Laboratory Standards Institute ; CV ; coefficient of variation ; HAMA ; human anti-mouse antibodies ; Ig ; immunoglobulin ; IL ; interleukin ; IPF ; idiopathic pulmonary fibrosis ; IUO ; Investigational Use Only ; kDa ; kilodalton ; LOQ ; limit of quantitation ; mAb ; monoclonal antibody ; NSCLC ; non-small-cell lung cancer ; PAGE ; polyacrylamide gel electrophoresis ; PEI ; polyethylenimine ; PVDF ; polyvinylidene difluoride ; RF ; rheumatoid factor
• 刊名：Clinica Chimica Acta
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：464
• 期：Complete
• 页码：228-235
• 全文大小：708 K
• 卷排序：464

文摘

The new automated periostin immunoassay is performed on the ARCHITECT i System. This Investigational Use Only assay reliably measures periostin concentrations. This assay detects periostin isoforms known to be expressed in the lung.