Three-dimensional imaging forced oscillation technique to assess position-dependent airway obstruction in relapsing polychondritis: A case report

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• 作者：Takahiro Kamada ; MD^a ; ^b ; ^{takahiro00920619@gmail.com} ; Isao Ito ; MD ; PhD ; FCCP^a ; ^{isaoito@kuhp.kyoto-u.ac.jp} ; Yoshihiro Kanemitsu ; MD ; PhD^a ; ^{kaney32@med.nagoya-cu.ac.jp} ; Susumu Sato ; MD ; PhD^a ; ^{ssato@kuhp.kyoto-u.ac.jp} ; Hisako Matsumoto ; MD ; PhD^a ; ^{hmatsumo@kuhp.kyoto-u.ac.jp} ; Akio Niimi ; MD ; PhD^a ; ^c ; ^{a.niimi@med.nagoya-cu.ac.jp} ; Michiaki Mishima ; MD ; PhD^a ; ^{mishima@kuhp.kyoto-u.ac.jp}
• 关键词：3D ; three-dimensional ; CT ; computed tomography ; FEV1 ; forced expiratory volume in one second ; FOT ; forced oscillation technique ; FVC ; forced vital capacity ; IOS ; impulse oscillation system ; OSAS ; obstructive sleep apnea syndrome ; PEFR ; peak expiratory flow rate ; PFT ; pulmonary function test ; RP ; relapsing polychondritis ; Rrs ; respiratory system resistance ; V25 ; flow rate at 25% of FVC ; V50 ; flow rate at 50% of FVC ; Xrs ; respiratory system reactance
• 刊名：Respiratory Investigation
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：55
• 期：1
• 页码：69-73
• 全文大小：1052 K
• 卷排序：55

文摘

Relapsing polychondritis (RP) is characterized by recurrent systemic inflammation of the cartilages and is accompanied by central airway collapse. We report a case wherein three-dimensional imaging of respiratory system resistance (Rrs) and respiratory system reactance (Xrs) by using MostGraph (CHEST M.I., Tokyo, Japan), a forced oscillation system, revealed that Rrs and Xrs in the inspiratory and expiratory phases correlated with proximal airway collapse. The degree of difference in Rrs and Xrs between the supine and sitting positions reflected airway collapse more closely than did the pulmonary function test. MostGraph could be a useful tool for assessing airway collapse in RP.