Synthesis of multi-functional nanocapsules via interfacial AGET ATRP in miniemulsion for tumor micro-environment responsive drug delivery

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Synthesis of multi-functional nanocapsules via interfacial AGET ATRP in miniemulsion for tumor micro-environment responsive drug delivery

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作者：Kun Tian ; Jin Zeng ; Xubo Zhao ; Lei Liu ; Xu Jia ; Peng Liu ; ^{pliu@lzu.edu.cn" class="auth_mail" title="E-mail the corresponding author}
关键词：Polymeric hollow nanocapsules ; Reduction-triggered ; pH responsive ; Targeted and controlled drug delivery ; AGET ATRP ; Miniemulsion interfacial polymerization
刊名：Colloids and Surfaces B: Biointerfaces
出版年：2015
出版时间：1 October 2015
年：2015
卷：134
期：Complete
页码：188-195
全文大小：1336 K

文摘

•: Multi-functional polymeric hollow nanocapsules were synthesized via AGET ATRP.
•: Folate group significantly improved their pH-responsive and DOX-loading capacity.
•: An acidic pH and presence of GSH would accelerate the DOX release behavior.

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