Impact of detergents on the physiochemical behavior of itraconazole loaded nanostructured lipid carriers

详细信息    查看全文

• 作者：A. Bhadra^a ; G. Karmakar^b ; P. Nahak^b ; P. Chettri^c ; B. Roy^b ; P. Guha^b ; A.K. Mandal^d ; R.K. Nath^e ; A.K. Panda^f ; ^{akpanda@mail.vidyasagar.ac.in} ; ^{akpanda1@yahoo.com}
• 关键词：NLC ; ITZ ; DLS ; DSC ; Drug release ; Antifungul activity
• 刊名：Colloids and Surfaces A: Physicochemical and Engineering Aspects
• 出版年：2017
• 出版时间：5 March 2017
• 年：2017
• 卷：516
• 期：Complete
• 页码：63-71
• 全文大小：3017 K
• 卷排序：516

文摘

NLCs were prepared with triolein, cetyl palmitate and palmitic acid. Cationic, anionic, zwitterionic and nonionic surfactants were used as stabilizers. Antifungal drug, itraconazole was loaded into NLC. Physicochemical characterizations of drug loaded NLCs were done. Drug loaded NLCs showed superior antifungul activities.