ar0005">Patients reporting moderate to severe symptoms of contact lens discomfort (CLD) can be helped by the use of nelfilcon A or delefilcon A daily disposable lenses.

ar0010">For those showing marginal CLD, refiting them in delefilcon A can improve their symptoms but nelfilcon A failed to make a significant reduction in their symptoms.

ar0015">Consequently, practitioners should base their clinical decision on symptoms as identified with validated questionnaires.

ar0020">CLD improvement is material dependant.

ar0025">Delefilcon A represents a better alternative to switch patients into daily disposable modality.