Rotenone causing dysfunctional mitochondria and lysosomes in cerebral ganglions of Lumbricus terrestris degenerate giant fibers and neuromuscular junctions

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Rotenone causing dysfunctional mitochondria and lysosomes in cerebral ganglions of Lumbricus terrestris degenerate giant fibers and neuromuscular junctions

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作者：Mamangam Subaraja ; Arambakkam Janardhanam Vanisree ; ^{vanielango@gmail.com" class="auth_mail" title="E-mail the corresponding author}
关键词：Rotenone ; Cerebral ganglions ; Neuropile ; Giant fibres ; Movement
刊名：Chemosphere
出版年：2016
出版时间：June 2016
年：2016
卷：152
期：Complete
页码：468-480
全文大小：3417 K

文摘

•: Rotenone causes structural and functional variations of organelle of cerebral ganglions of worms.
•: Giant fibers and neuromuscular junctions were targeted by rotenone affecting the locomotion.
•: Dopaminergic and cholinergic pathways are also impaired by rotenone in worms.
•: Bioaccumulation factor of 0.28–0.32 ppm/μg cause degeneration of cerebral ganglions.

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